| Date |
|
Score |
|
Score |
|
|
| 2008-09-04 | Perry Traditional Acad. (PA) | 30 | Schenley (PA) ** | 16 | | |
| 2008-09-05 | Calhoun County | 37 | Ritchie County ** | 25 | | |
| 2008-09-05 | Clay-Battelle | 19 | Bishop Donahue ** | 8 | | |
| 2008-09-05 | Doddridge County ** | 21 | Valley-Fayette | 20 | | |
| 2008-09-05 | Fayetteville ** | 40 | Midland Trail | 21 | | |
| 2008-09-05 | Madonna ** | 42 | Hundred | 13 | | |
| 2008-09-05 | Man ** | 54 | Mt. View | 6 | | |
| 2008-09-05 | Meadow Bridge | 42 | Williamson ** | 20 | | |
| 2008-09-05 | Mt. Hope | 28 | Oak Hill ** | 20 | | |
| 2008-09-05 | Notre Dame | 18 | Valley-Wetzel ** | 12 | | |
| 2008-09-05 | Paden City ** | 36 | Bellaire St.John (OH) | 19 | | |
| 2008-09-05 | Pendleton County | 46 | Petersburg ** | 14 | | |
| 2008-09-05 | Pocahontas County ** | 41 | Shady Spring | 34 | | |
| 2008-09-05 | South Harrison ** | 49 | Gilmer County | 7 | | |
| 2008-09-05 | St. Marys ** | 34 | Wirt County | 7 | | |
| 2008-09-05 | Tucker County | 41 | Tygarts Valley ** | 0 | | |
| 2008-09-05 | Van ** | 62 | Hannan | 24 | | |
| 2008-09-05 | Wahama ** | 47 | Reedsville Eastern (OH) | 19 | | |
| 2008-09-05 | Wheeling Central ** | 21 | John Adams (OH) | 0 | | |
| 2008-09-05 | Williamstown | 25 | Magnolia ** | 22 | | |
| 2008-09-05 | Braxton County ** | 19 | Clay County | 12 | | |
| 2008-09-05 | Chapmanville ** | 24 | Herbert Hoover | 0 | | |
| 2008-09-05 | Frankfort | 49 | Liberty-Harrison ** | 14 | | |
| 2008-09-05 | Grafton ** | 45 | Lewis County | 15 | | |
| 2008-09-05 | Greenbrier West ** | 55 | Richwood | 0 | | |
| 2008-09-05 | Independence | 37 | Sherman ** | 31 | | |
| 2008-09-05 | Keyser | 41 | Moorefield ** | 0 | | |
| 2008-09-05 | Liberty-Raleigh ** | 36 | Summers County | 26 | | |
| 2008-09-05 | Philip Barbour | 27 | Lincoln ** | 7 | | |
| 2008-09-05 | PikeView ** | 34 | Iaeger | 26 | | |
| 2008-09-05 | Pt. Pleasant ** | 42 | Sissonville | 10 | | |
| 2008-09-05 | Ravenswood ** | 35 | Poca | 6 | | |
| 2008-09-05 | Scott | 35 | Wyoming East ** | 14 | | |
| 2008-09-05 | Tolsia ** | 21 | Webster County | 0 | | |
| 2008-09-05 | Tyler Consolidated | 14 | Roane County ** | 7 | | |
| 2008-09-05 | Wayne | 31 | James Monroe ** | 10 | | |
| 2008-09-05 | Weir | 23 | Edison Local (OH) ** | 7 | | |
| 2008-09-05 | Westside ** | 28 | Gilbert | 20 | | |
| 2008-09-05 | Bridgeport ** | 35 | Robert C. Byrd | 26 | | |
| 2008-09-05 | Brooke ** | 48 | Anacostia (DC) | 14 | | |
| 2008-09-05 | Capital ** | 21 | Cabell Midland | 7 | | |
| 2008-09-05 | Fairmont Sr. | 41 | North Marion ** | 6 | | |
| 2008-09-05 | Hampshire ** | 13 | Berkeley Springs | 6 | | |
| 2008-09-05 | Jefferson | 42 | Park View-Sterling (VA) ** | 36 | | |
| 2008-09-05 | Lincoln County | 18 | Winfield ** | 14 | | |
| 2008-09-05 | Martinsburg | 23 | Turner Ashby (VA) ** | 21 | | |
| 2008-09-05 | Morgantown ** | 56 | Elkins | 19 | | |
| 2008-09-05 | Nicholas County | 28 | Buckhannon-Upshur ** | 7 | | |
| 2008-09-05 | Princeton | 15 | Bluefield ** | 13 | | |
| 2008-09-05 | Ripley ** | 28 | Greenbrier East | 26 | | |
| 2008-09-05 | Riverside | 26 | Huntington ** | 23 | | |
| 2008-09-05 | South Charleston ** | 13 | George Washington | 12 | | |
| 2008-09-05 | Spring Valley | 44 | St. Albans ** | 14 | | |
| 2008-09-05 | University | 42 | East Fairmont ** | 17 | | |
| 2008-09-05 | Wheeling Park | 26 | Zanesville (OH) ** | 7 | | |
| 2008-09-05 | Woodrow Wilson ** | 31 | Parkersburg | 20 | | |
| 2008-09-05 | Calvin Coolidge (DC) ** | 20 | Friendship Collegiate (DC) | 18 | | |
| 2008-09-05 | Wilson (DC) | 44 | Spingarn (DC) ** | 0 | | |
| 2008-09-05 | Berea (KY) ** | 12 | Pineville (KY) | 7 | | |
| 2008-09-05 | Clark (KY) | 29 | Fairland (OH) ** | 28 | | |
| 2008-09-05 | Hazard (KY) ** | 47 | Pike Central (KY) | 13 | | |
| 2008-09-05 | Jackson County (KY) | 30 | Betsy Layne (KY) ** | 20 | | |
| 2008-09-05 | Boonsboro (MD) ** | 26 | Crossland (MD) | 14 | | |
| 2008-09-05 | Century (MD) ** | 38 | South Hagerstown (MD) | 0 | | |
| 2008-09-05 | Fort Hill (MD) ** | 14 | City College (MD) | 6 | | |
| 2008-09-05 | Mt. Ridge (MD) ** | 55 | Sidwell Friends (MD) | 14 | | |
| 2008-09-05 | Potomac (MD) | 42 | McKinley (DC) ** | 0 | | |
| 2008-09-05 | Smithburg (MD) ** | 27 | Northern Garrett County (MD) | 21 | | |
| 2008-09-05 | Urbana (MD) ** | 6 | Lackey (MD) | 3 | | |
| 2008-09-05 | Charlotte Country Day Sch (NC) | 14 | Charlotte Catholic (NC) ** | 10 | | |
| 2008-09-05 | Beallsville (OH) ** | 51 | Cameron | 14 | | |
| 2008-09-05 | Bloom-Carroll (OH) ** | 27 | Athens (OH) | 13 | | |
| 2008-09-05 | Caldwell (OH) | 35 | Barnesville (OH) ** | 12 | | |
| 2008-09-05 | Chesapeake (OH) ** | 48 | Symmes Valley (OH) | 6 | | |
| 2008-09-05 | Claymont (OH) | 21 | Carrollton (OH) ** | 7 | | |
| 2008-09-05 | Columbiana Crestview (OH) | 55 | Oak Glen ** | 20 | | |
| 2008-09-05 | Frontier (OH) ** | 26 | Buckeye Trail (OH) | 22 | | |
| 2008-09-05 | Girard (OH) | 35 | Warren JFK (OH) ** | 27 | | |
| 2008-09-05 | Green (OH) ** | 27 | Burch | 24 | | |
| 2008-09-05 | Indian Creek (OH) | 47 | East Cleveland (OH) ** | 0 | | |
| 2008-09-05 | Ironton (OH) ** | 42 | Gallia Academy (OH) | 6 | | |
| 2008-09-05 | Portsmouth West (OH) ** | 28 | South Point (OH) | 7 | | |
| 2008-09-05 | River (OH) | 27 | Monroe Central (OH) ** | 6 | | |
| 2008-09-05 | South Gallia (OH) | 14 | Racine Southern (OH) ** | 0 | | |
| 2008-09-05 | Southern Salineville (OH) | 55 | Toronto (OH) ** | 0 | | |
| 2008-09-05 | St. Clairsville (OH) | 28 | Union Local (OH) ** | 14 | | |
| 2008-09-05 | Steubenville (OH) ** | 45 | East Liverpool (OH) | 14 | | |
| 2008-09-05 | Warren Local (OH) ** | 14 | Parkersburg South | 7 | | |
| 2008-09-05 | West Muskingum (OH) ** | 21 | Morgan (OH) | 0 | | |
| 2008-09-05 | Greencastle Atrium (PA) | 19 | West Perry (PA) ** | 10 | | |
| 2008-09-05 | State College (PA) | 17 | Cumberland Valley (PA) ** | 14 | | |
| 2008-09-05 | Westinghouse (PA) | 24 | Oliver (PA) ** | 6 | | |
| 2008-09-05 | Grace Christian (TN) | 50 | Unaka (TN) ** | 7 | | |
| 2008-09-05 | Bath County (VA) ** | 27 | East Hardy | 26 | | |
| 2008-09-05 | Bland (VA) | 50 | Auburn (VA) ** | 43 | | |
| 2008-09-05 | Eastern Montgomery (VA) ** | 44 | Galax (VA) | 20 | | |
| 2008-09-05 | Fauquier (VA) ** | 52 | Kettle Run (VA) | 6 | | |
| 2008-09-05 | Ft. Chiswell (VA) ** | 17 | Northwood (VA) | 0 | | |
| 2008-09-05 | Grundy (VA) ** | 48 | East Ridge (KY) | 6 | | |
| 2008-09-05 | Handley (VA) | 49 | Loudoun County (VA) ** | 21 | | |
| 2008-09-05 | Haysi (VA) | 22 | Tug Valley ** | 6 | | |
| 2008-09-05 | Heritage (VA) ** | 56 | North Hagerstown (MD) | 28 | | |
| 2008-09-05 | Honaker (VA) ** | 38 | Twin Valley (VA) | 0 | | |
| 2008-09-05 | Hurley (VA) | 48 | Montcalm ** | 14 | | |
| 2008-09-05 | James Wood (VA) ** | 31 | Washington | 0 | | |
| 2008-09-05 | Narrows (VA) ** | 48 | Craig County (VA) | 7 | | |
| 2008-09-05 | Potomac Falls (VA) | 68 | Hedgesville ** | 0 | | |
| 2008-09-05 | Powell Valley (VA) | 34 | Richlands (VA) ** | 7 | | |
| 2008-09-05 | Rappahannock County (VA) | 7 | Hancock (MD) ** | 0 | | |
| 2008-09-05 | Roanoke Catholic (VA) | 54 | Brunswick Academy (VA) ** | 22 | | |
| 2008-09-05 | Sherando (VA) | 37 | Musselman ** | 10 | | |
| 2008-09-05 | Spotsylvania (VA) | 28 | Manassas Park (VA) ** | 14 | | |
| 2008-09-05 | St. Paul (VA) | 18 | Ervinton (VA) ** | 14 | | |
| 2008-09-05 | Woodstock Central (VA) ** | 29 | Strasburg (VA) | 0 | | |
| 2008-09-06 | Matewan ** | 19 | Sciotoville Community (OH) | 6 | | |
| 2008-09-06 | Parkersburg Catholic ** | 26 | Buffalo | 0 | | |
| 2008-09-06 | Allegany (MD) ** | 52 | Southern Garrett County (MD) | 8 | | |
| 2008-09-06 | Bridgeport (OH) | 41 | Conotton Valley (OH) ** | 13 | | |
| 2008-09-06 | Buckeye Local (OH) | 25 | Bellaire (OH) ** | 22 | | |
| 2008-09-06 | East Palestine (OH) ** | 42 | Steubenville Central (OH) | 22 | | |
| 2008-09-06 | Shadyside (OH) ** | 21 | Linsly (WV) | 14 | | |
| 2008-09-06 | Brashear (PA) ** | 48 | Langley (PA) | 14 | | |
| 2008-09-06 | Blacksburg (VA) | 35 | Graham (VA) ** | 10 | | |