| Date |
|
Score |
|
Score |
|
|
| 2008-10-16 | Walkersville (MD) | 30 | North Hagerstown (MD) ** | 22 | | |
| 2008-10-16 | Schenley (PA) ** | 46 | Allderdice (PA) | 18 | | |
| 2008-10-17 | Big Creek | 38 | Twin Valley (VA) ** | 14 | | |
| 2008-10-17 | Buffalo | 44 | Clay County ** | 20 | | |
| 2008-10-17 | Calhoun County ** | 13 | Roane County | 0 | | |
| 2008-10-17 | Clay-Battelle ** | 15 | Cameron | 9 | | |
| 2008-10-17 | Fayetteville ** | 35 | Mt. Hope | 33 | | |
| 2008-10-17 | Gilmer County | 39 | Hundred ** | 18 | | |
| 2008-10-17 | Man | 35 | Gilbert ** | 12 | | |
| 2008-10-17 | Meadow Bridge | 46 | Van ** | 12 | | |
| 2008-10-17 | Midland Trail ** | 21 | Sherman | 0 | | |
| 2008-10-17 | Moorefield ** | 71 | East Hardy | 0 | | |
| 2008-10-17 | Parkersburg Catholic | 46 | Bellaire St.John (OH) ** | 0 | | |
| 2008-10-17 | Pocahontas County ** | 59 | Tygarts Valley | 6 | | |
| 2008-10-17 | Richwood ** | 40 | Hannan | 18 | | |
| 2008-10-17 | St. Marys | 21 | South Harrison ** | 7 | | |
| 2008-10-17 | Tucker County | 37 | Pendleton County ** | 16 | | |
| 2008-10-17 | Williamson ** | 60 | Burch | 0 | | |
| 2008-10-17 | Williamstown ** | 46 | Wahama | 13 | | |
| 2008-10-17 | Wirt County ** | 29 | Valley-Wetzel | 14 | | |
| 2008-10-17 | Bluefield | 47 | Mt. View ** | 8 | | |
| 2008-10-17 | Chapmanville | 45 | Tug Valley ** | 8 | | |
| 2008-10-17 | Frankfort ** | 55 | Petersburg | 0 | | |
| 2008-10-17 | Grafton ** | 51 | Robert C. Byrd | 7 | | |
| 2008-10-17 | Independence ** | 39 | Liberty-Raleigh | 6 | | |
| 2008-10-17 | James Monroe ** | 21 | Greenbrier East | 14 | | |
| 2008-10-17 | Keyser | 55 | Southern Garrett County (MD) ** | 8 | | |
| 2008-10-17 | Magnolia ** | 28 | Barnesville (OH) | 0 | | |
| 2008-10-17 | Oak Glen ** | 48 | Liberty-Harrison | 7 | | |
| 2008-10-17 | Ravenswood ** | 24 | Pt. Pleasant | 21 | 1 OT | |
| 2008-10-17 | Ritchie County | 23 | Doddridge County ** | 14 | | |
| 2008-10-17 | Scott | 31 | Shady Spring ** | 20 | | |
| 2008-10-17 | Summers County ** | 38 | Valley-Fayette | 14 | | |
| 2008-10-17 | Tyler Consolidated | 46 | Braxton County ** | 0 | | |
| 2008-10-17 | Wayne | 21 | Tolsia ** | 18 | | |
| 2008-10-17 | Webster County ** | 29 | Greenbrier West | 21 | | |
| 2008-10-17 | Westside ** | 23 | Wyoming East | 20 | | |
| 2008-10-17 | Bridgeport | 35 | Lincoln ** | 7 | | |
| 2008-10-17 | Cabell Midland ** | 35 | Nitro | 6 | | |
| 2008-10-17 | Capital ** | 21 | Princeton | 20 | | |
| 2008-10-17 | Fairmont Sr. ** | 41 | Elkins | 21 | | |
| 2008-10-17 | George Washington | 42 | Parkersburg ** | 14 | | |
| 2008-10-17 | Jefferson | 34 | Hedgesville ** | 0 | | |
| 2008-10-17 | Lewis County | 30 | Philip Barbour ** | 26 | | |
| 2008-10-17 | Logan ** | 24 | Sissonville | 21 | | |
| 2008-10-17 | Martinsburg ** | 28 | Friendship Collegiate (DC) | 22 | | |
| 2008-10-17 | Morgantown ** | 61 | Brooke | 15 | | |
| 2008-10-17 | Musselman ** | 42 | Hampshire | 12 | | |
| 2008-10-17 | Nicholas County ** | 41 | Oak Hill | 6 | | |
| 2008-10-17 | Preston ** | 27 | East Fairmont | 12 | | |
| 2008-10-17 | South Charleston | 21 | Hurricane ** | 14 | | |
| 2008-10-17 | Spring Valley | 20 | Lincoln County ** | 14 | | |
| 2008-10-17 | St. Albans | 34 | Huntington ** | 20 | | |
| 2008-10-17 | University | 51 | John Marshall ** | 7 | | |
| 2008-10-17 | Wheeling Park ** | 41 | East Liverpool (OH) | 6 | | |
| 2008-10-17 | Winfield | 33 | Poca ** | 12 | | |
| 2008-10-17 | Woodrow Wilson | 28 | Riverside ** | 8 | | |
| 2008-10-17 | Calvin Coolidge (DC) ** | 40 | Wilson (DC) | 14 | | |
| 2008-10-17 | McKinley (DC) | 21 | Anacostia (DC) ** | 14 | | |
| 2008-10-17 | Spingarn (DC) ** | 2 | Eastern (DC) | 0 | | |
| 2008-10-17 | Belfry (KY) ** | 56 | Pike Central (KY) | 7 | | |
| 2008-10-17 | Berea (KY) | 27 | Kentucky Country Day (KY) ** | 20 | | |
| 2008-10-17 | Powell County (KY) | 60 | Betsy Layne (KY) ** | 14 | | |
| 2008-10-17 | Shelby Valley (KY) ** | 59 | Appalachia (VA) | 6 | | |
| 2008-10-17 | Allegany (MD) | 55 | Washington ** | 13 | | |
| 2008-10-17 | Boonsboro (MD) | 48 | Brunswick (MD) ** | 28 | | |
| 2008-10-17 | Fort Hill (MD) ** | 14 | Douglass (MD) | 12 | | |
| 2008-10-17 | Mt. Ridge (MD) ** | 42 | Berkeley Springs | 0 | | |
| 2008-10-17 | Smithburg (MD) | 7 | South Hagerstown (MD) ** | 0 | | |
| 2008-10-17 | Urbana (MD) ** | 28 | Gwynn Park (MD) | 27 | 1 OT | |
| 2008-10-17 | Charlotte Country Day Sch (NC) | 21 | Charlotte Christian (NC) ** | 3 | | |
| 2008-10-17 | Athens (OH) | 33 | Belpre (OH) ** | 18 | | |
| 2008-10-17 | Beallsville (OH) ** | 50 | Paden City | 8 | | |
| 2008-10-17 | Buckeye Local (OH) ** | 18 | Edison Local (OH) | 14 | | |
| 2008-10-17 | Cambridge (OH) | 34 | Claymont (OH) ** | 17 | | |
| 2008-10-17 | Chillicothe (OH) ** | 57 | Warren Local (OH) | 7 | | |
| 2008-10-17 | Columbiana Crestview (OH) | 41 | Springfield NM (OH) ** | 7 | | |
| 2008-10-17 | Fairland (OH) | 53 | Chesapeake (OH) ** | 20 | | |
| 2008-10-17 | John Adams (OH) | 46 | Lincoln West (OH) ** | 0 | | |
| 2008-10-17 | Monroe Central (OH) | 59 | Frontier (OH) ** | 7 | | |
| 2008-10-17 | Oak Hill (OH) ** | 54 | South Gallia (OH) | 0 | | |
| 2008-10-17 | Philo (OH) | 21 | Morgan (OH) ** | 20 | | |
| 2008-10-17 | River (OH) | 49 | Buckeye Trail (OH) ** | 7 | | |
| 2008-10-17 | Sciotoville Community (OH) | 33 | Green (OH) ** | 7 | | |
| 2008-10-17 | South Point (OH) ** | 55 | Rock Hill (OH) | 16 | | |
| 2008-10-17 | St. Clairsville (OH) ** | 28 | Steubenville Central (OH) | 13 | | |
| 2008-10-17 | Steubenville (OH) ** | 47 | Wheeling Central | 22 | | |
| 2008-10-17 | Trimble (OH) | 71 | Racine Southern (OH) ** | 28 | | |
| 2008-10-17 | Waterford (OH) ** | 34 | Reedsville Eastern (OH) | 6 | | |
| 2008-10-17 | Zanesville (OH) | 12 | Gallia Academy (OH) ** | 0 | | |
| 2008-10-17 | Chestnut Ridge (PA) ** | 28 | Northern Garrett County (MD) | 8 | | |
| 2008-10-17 | Greencastle Atrium (PA) ** | 24 | Northern York (PA) | 16 | | |
| 2008-10-17 | Langley (PA) ** | 29 | Carrick (PA) | 14 | | |
| 2008-10-17 | Rockwood (PA) | 34 | Hancock (MD) ** | 6 | | |
| 2008-10-17 | State College (PA) | 34 | Altoona (PA) ** | 13 | | |
| 2008-10-17 | Cloudland (TN) ** | 33 | Unaka (TN) | 0 | | |
| 2008-10-17 | Bath County (VA) | 34 | McCluer (VA) ** | 16 | | |
| 2008-10-17 | Bland (VA) ** | 14 | Narrows (VA) | 7 | | |
| 2008-10-17 | Briar Woods (VA) ** | 14 | Park View-Sterling (VA) | 6 | | |
| 2008-10-17 | Broad Run (VA) | 37 | Loudoun County (VA) ** | 17 | | |
| 2008-10-17 | Carroll County (VA) | 41 | Grundy (VA) ** | 7 | | |
| 2008-10-17 | Coeburn (VA | 49 | St. Paul (VA) ** | 27 | | |
| 2008-10-17 | Craig County (VA) ** | 34 | Covington (VA) | 20 | | |
| 2008-10-17 | Eastern View (VA) ** | 47 | Mason (VA) | 28 | | |
| 2008-10-17 | Ft. Chiswell (VA) ** | 47 | Galax (VA) | 6 | | |
| 2008-10-17 | Haysi (VA) ** | 55 | Hurley (VA) | 6 | | |
| 2008-10-17 | James Wood (VA) | 17 | Sherando (VA) ** | 14 | | |
| 2008-10-17 | Manassas Park (VA) | 27 | Strasburg (VA) ** | 12 | | |
| 2008-10-17 | Potomac Falls (VA) ** | 54 | Freedom (VA) | 0 | | |
| 2008-10-17 | Roanoke Catholic (VA) ** | 41 | Fuqua (VA) | 7 | | |
| 2008-10-17 | Turner Ashby (VA) ** | 40 | Rockbridge County (VA) | 20 | | |
| 2008-10-17 | Warren County (VA) ** | 30 | Woodstock Central (VA) | 14 | | |
| 2008-10-18 | Bishop Donahue ** | 45 | Notre Dame | 28 | | |
| 2008-10-18 | Madonna ** | 47 | Toronto (OH) | 6 | | |
| 2008-10-18 | Bellaire (OH) ** | 17 | Indian Creek (OH) | 7 | | |
| 2008-10-18 | Portsmouth Notre Dame (OH) ** | 26 | Symmes Valley (OH) | 20 | | |
| 2008-10-18 | Shadyside (OH) | 35 | Bridgeport (OH) ** | 6 | | |
| 2008-10-18 | Warren JFK (OH) ** | 47 | Southview (OH) | 0 | | |
| 2008-10-18 | Brashear (PA) | 33 | Oliver (PA) ** | 14 | | |